ccca_ajaxhandler.php in Trend Micro Smart Protection Server 2.5 before build 2200, 2.6 before build 2106, and 3.0 before build 1330 allows remote authenticated users to execute arbitrary commands via shell metacharacters in the (1) host or (2) apikey parameter in a register action, (3) enable parameter in a save_stting action, or (4) host or (5) apikey parameter in a test_connection action.